Zhiyu Chen
Zhiyu Chen — researcher or builder tracked in the Angestrom contributor network.
Papers · 2
Towards Precision Therapy in Hepatocellular Carcinoma: A Clinical-Reasoning LLM for Risk Stratification and Treatment Guidance
Hepatocellular carcinoma (HCC) is a common malignancy and a leading cause of cancer-related mortality. Current guidelines and staging systems provide coarse categories, but often miss within-stage heterogeneity and the clinical context in electronic medical records (EMRs). We present HCC-STAR (Hepatocellular Carcinoma Staging, Treatment And pRognosis), a clinically aligned large language model that reads routine EMR narratives and jointly outputs risk score-based staging, ranked guideline-consistent treatments with evidence-based rationales, and individualized survival estimates. We curated ab
Rule-Compliant Visual Spatial Planning for Multimodal Large Language Models
Multimodal large language models (MLLMs) combine linguistic reasoning with visual perception, yet their ability to perform visual spatial planning under explicit or previously unseen rule constraints remains underexplored. This setting requires models to jointly understand spatial layouts, interpret natural-language rules, and plan valid actions accordingly. To address this gap, we introduce RuleMaze, a controllable benchmark in which MLLMs must navigate mazes while obeying natural-language rules of varying complexity. RuleMaze isolates rule-compliant spatial planning by requiring accurate per