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CenSynCMB: Centre Maps and Physics-Guided Synthesis for Microbleed Detection

Cerebral microbleeds (CMBs) are MRI markers of small vessel disease and the microbleed component of amyloid related imaging abnormalities (ARIA-H), but their small size, sparsity, and similarity to vessels, calcification-like foci, and artefacts make automated detection difficult. We propose CenSynCMB, a centre-guided and mimic-aware framework combining a 3D Attention U-Net, auxiliary centre-map supervision, false-negative-driven reweighting, and fold-wise physics-guided synthesis of positive CMBs and labelled hard negatives. Synthetic data expose the detector to compact lesions and common mim

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  • PossiblePossibly related (embedding) · 45%DIAGNijmegen/rse-grand-challenge
  • LinkedLinked via arxiv author · 85%Lucas He

    CenSynCMB: Centre Maps and Physics-Guided Synthesis for Microbleed Detection

  • LinkedLinked via arxiv author · 85%Hanyuan Zhang

    CenSynCMB: Centre Maps and Physics-Guided Synthesis for Microbleed Detection

  • LinkedLinked via arxiv author · 85%Krinos Li

    CenSynCMB: Centre Maps and Physics-Guided Synthesis for Microbleed Detection

  • LinkedLinked via arxiv author · 85%Adama Fatima Saccoh

    CenSynCMB: Centre Maps and Physics-Guided Synthesis for Microbleed Detection

  • LinkedLinked via arxiv author · 85%Silvia Ingala

    CenSynCMB: Centre Maps and Physics-Guided Synthesis for Microbleed Detection

  • LinkedLinked via arxiv author · 85%Rafael Rehwald

    CenSynCMB: Centre Maps and Physics-Guided Synthesis for Microbleed Detection

  • LinkedLinked via arxiv author · 85%Marleen de Bruijne

    CenSynCMB: Centre Maps and Physics-Guided Synthesis for Microbleed Detection

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