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paperarXivTrust 82 · PrimaryPublished 20h agoLive · 3h ago

DistillPath: An Efficient 22M Distilled Pathology Encoder Approaching Large Foundation Model Performance

Many high-performing pathology tile encoders are now foundation models with hundreds of millions to over a billion parameters. Encoding and storing the thousands of tiles in each whole-slide image with such models is costly on commodity hardware, so compact encoders that retain useful downstream performance are a valuable alternative. We present DistillPath-KS16, which starts from the existing 22M kaiko ViT-S/16 encoder and improves it by distilling from released pathology encoders used as frozen teachers. The recipe reads only the teachers' final class and patch tokens and trains on 6,000 pub

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