Multi-Large Language Model Orchestrated Severity Assessment of Clinical Records (MOSAIC)
Background: Disease severity is a multidimensional construct difficult to capture with rule-based approaches in Electronic Healthcare Records (EHR). Agentic large language model (LLM) systems could synthesise clinical evidence and reason over EHRs, but remain unevaluated for this task. Methods: MOSAIC is a two-phase agentic LLM framework for severity phenotyping, using type 2 diabetes (T2D) as a proof-of-concept. MOSAIC was evaluated on a synthetic cohort (SyntheticMass; open-weight N = 4,886; closed-weight N = 200) against three algorithmic ground truths (DCSI, DiSSCo, Cooper) and against all
Lineage graph
Paper → model → repo connections mined from source citations (Tier-1 exact match).
Why these links exist
Every edge carries a method, confidence, and the source snippet that justified it — so bad links are debuggable.
- PossiblePossibly related (embedding) · 61%Towards AI-augmented decision making in psychiatry →
- PossiblePossibly related (embedding) · 60%Clinical drug report generation using multi-phase prompt large language models - Nature →
- PossiblePossibly related (embedding) · 52%tyang816/Awesome-TCM-LLM →
- PossiblePossibly related (embedding) · 51%Co-pilot, Not Autopilot: A Practical Method for Using Large Language Models in Interventional Cardiology - EMJ →
- PossiblePossibly related (embedding) · 50%Emo-gml/Awesome-Mental-Health-LLMs →
- PossiblePossibly related (embedding) · 51%AI Model Predicts 348 Diseases from Electronic Health Record, Genetics - Inside Precision Medicine →
- PossiblePossibly related (embedding) · 60%Addressing benchmarking gaps in large language models for health and medicine with dynamic red-teaming - Nature →
- PossiblePossibly related (embedding) · 51%A knowledge-enhanced domain-aware large language model agent for atrial fibrillation management - Nature →
