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paperarXivTrust 82 · PrimaryPublished 24d agoLive · 21d ago

Toward Generalizable Cognitive Impairment Detection with Speech-Based Multimodal Large Language Models

Cognitive impairment (CI) is a growing public health concern. Early and accurate diagnosis is critical for enabling timely intervention and improving patient outcomes. Speech-based CI detection has emerged as a promising non-invasive approach, as speech signals encode both linguistic and acoustic markers associated with cognitive decline. Recent advances in large language models (LLMs) further strengthen the potential of speech-based assessment by enabling more expressive representation learning and improved generalization across diverse speakers, recording devices, and clinical environments.

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